Medical marijuana has emerged as a treatment for painful gastrointestinal conditions that include intestinal inflammation and spasms. These diseases include colitis, JWH-018 zum Verkauf online Crohn’s disease and inflammatory bowel syndrome (IBS). Patients with these diseases can often experience cramps, inflammation, chronic pain, weight loss, and diarrhea. Medical marijuana is often able to provide significant relief from these symptoms.
Crohn’s disease is a chronic inflammatory autoimmune disease of the gut that causes intense, severe pain. The cause is unknown. Digestion is affected and in very rare cases can be fatal. The disease is destructive to the intesting . Over 500,000 people in the United States suffer from Crohn’s disease . In most states that have legalized medical marijuana, Crohn’s disease is an accepted condition for use.
Traditional medications that are used for Crohn’s disease include immunosuppressive drugs such as Imuran , Methotrexate , 6MP, steroids, mesalamine and Remicade . These drugs can cause the same symptoms as the disease, including nausea, vomiting, abdominal pain, and diarrhea. Steroids have some side effects that can include adrenal dysfunction, bone loss, ulcers, and glucose intolerance.
Various studies have shown promising results for medical marijuana in relieving the symptoms of gastrointestinal disorders such as Crohn’s disease .
A 2005 study published in O’Shaughnessy’s found that cannabis was very helpful with the symptoms of Crohn’s disease . There was a pilot study of marijuana at the Society of Cannabis Clinicians in a dozen patients with Crohn’s disease, and patients reported significant improvements in appetite, nausea, fatigue, vomiting, and depression. There were fewer flare-ups and fewer bowel movements per day. Patients were also able to reduce the amount of immunosuppressive medication needed.
Cannabinoids and the Gastrointestinal
Another 2001 study entitled Cannabinoids and the Gastrointestinal Tract found that the cannabinoids found in marijuana represent a potentially excellent option for the treatment of numerous GI disorders – including inflammatory bowel disease, functional bowel disease, gastroesophageal reflux disease, secretory diarrhea, stomach ulcers, and colon cancer. There are receptors in both the brain and GI system called CB1 receptors. In animals, the study showed that agonists for these receptors delayed gastric emptying and inhibited gastric acid secretion. CB1 receptors are mainly located in the brain.
A 2006 study published in the Journal of Endocrinolog JWH-018 zum Verkauf online Investigation shows that activation of the CB1 and CB2 cannabinoid receptors exert biological functions on the gastrointestinal tract.
There are CB2 receptors in numerous cells outside the brain, including in the lining of the gastrointestinal tract. Marijuana contains cannabinoids that activate the CB2 receptor – this is believed to reduce inflammation in the gastrointestinal tract, reducing pain and swelling. There is another compound in cannabis called beta- caryophyllene that also activates the CB-2 receptors.
It is broken down by the stomach and absorbed
Tonics and tinctures are made when marijuana is steeped in an alcohol resolution, which transfers the cannabinoids into the liquid. The tincture can then be rubbed onto the pores and skin, dripped, or sprayed within the mouth, and in addition added to foods and drinks recipes. Medical marijuana additionally comes within the type of ready-made candies and numerous different candies, all in CBD-rich types. Nonetheless, as with all medicines, the attractively packaged objects must be stored out of the attain of youngsters.
Marijuana is myrcene
The most common terpene found in marijuana is myrcene . It’s earthy, fruity, citrus and mango in quality. This terpene is a powerful antibiotic, anti-inflammatory and pain reliever. It is believed to work in combination with THC, relieving depression, elevating mood and allowing more THC to reach the brain.
Another terpene , beta- caryophyllene , smells peppery. It retains analgesic properties but has no mental effects. So it is considered non-psychoactive. Pinene is another terpene that is a main component of turpentine. It has a pine scent and has been shown to increase concentration, self-satisfaction, and memory. Terpenol smells floral with hints of orange blossom. It has a distinctly sedative effect and is great for sleeping issues.
There are other terpenes that help with memory enhancement, which is something that is usually thought to be adversely affected by existing marijuana strains. One of these is Pulgone , which slows down the destruction of memory transmission proteins. It helps keep people alert.
Cannabinoids in medical marijuana have the identical results because the cannabinoids already present in each human being. The human physique naturally produces its personal cannabinoids which are much like these present in marijuana. Brown College researchers have proven that the mind produces anandamide , a ache -killing cannabinoid . This naturally produced chemical impacts the CB1 and CB2 cannabinoid receptors of the human nervous and immune methods, respectively. These cannabinoids regulate physiological processes resembling urge for food, ache notion, temper and reminiscence. In addition they regulate sleep patterns and act as pure inflammatory brokers. Medical marijuana CBD is thought for its means to behave as an antioxidant within the mind. German researchers have discovered that cannabinoids are in a position not solely to cleanse broken mind cells, but additionally to stimulate the manufacturing of recent mind cells. This has led to analysis into high-CBD marijuana to deal with concussions in skilled athletes. With the added CBD from medical marijuana, sufferers may be handled for a wide range of different illnesses and situations. The marijuana may be prescribed for something from a easy lack of urge for food to pain-induced a number of sclerosis; as a result of usually those produced by the physique aren’t sufficient.